After a few years, while their marriage stays strong, it also slows down. Sam is gone more often for work and things only get worse when she finds out his colleague was behind the murder off her boss and the bomb in his office, leaving her out of work until further notice.
She definitely isn't pleased but tries to make things work nonetheless. However, not too long later, Sam comes home early in the morning, badly injured and Louise makes it clear she wants him to quit and find a normal, safe job. He won't listen, though which further widens the gap between them.
1935
Years pass and Sam is gone more often than he already was, his work seemingly demanding all his time. Meanwhile, Louise suffers from a miscarriage and isn't sure how to tell him, eventually deciding not to. They don't spend as much time with each other anymore, and when they do it usually ends with Louise putting her own feelings aside for him.
1938
After a rough and loud fight, Sam finally promises to do better, especially upon hearing about Louise's miscarriage. And he does. He actually spends more time at home but at the same time is planning to leave Salieri, no matter the cost - even at the cost of his friends.
A while later, she happily announces she's pregnant again and it only motivates him further. He helps Salieri get a new deal, with supposed 'diamonds' - at leasts, that's the excuse he uses to Paulie and Tommy. Instead, they're smuggling drugs, which the two are not pleased about. It makes the decision to go for a bank robbery all the more clearer for Paulie.
Sam is not pleased about the betrayal when he hears about it and visits Paulie later that evening, planning his great escape. After shooting him, leaving him for death and taking the money Paulie and Tommy had stolen, Sam plans on where to go with Louise, ready to leave the life he built behind for a white picket fence life.
His assassination attempt on Tommy, however, goes wrong and Tommy is fast to fight back. With some of the money made of the drug deal, he bought a bit of extra protection but Tommy managed to kill them all.
Sam attempts to convince Tommy to let him live, but fails, resulting in his death.
Not long after Sam's body is found, his funeral is arranged. Attended by a heavily pregnant Louise and his former colleagues. Louise definitely isn't pleased by the Don's attendance and tells him so. Tommy is the last to speak to her at the funeral, giving her part of the money Sam had stolen from him, lying that it was his last dying wish and forcing Louise to take it.
She uses the money to move out of Lost Heaven, moving to a bigger city to finally make something out of her music career. She gave birth to a healthy baby boy she names after Sam and her father.
She has a decent musical career, earning herself some hit songs. Her family ends up doing well, too. Her son married a woman and gave Louise several grandchildren. She quietly passed away in her sleep at the age of 72.
Louise slapped Don Salieri at Sam's funeral